The skin is the biggest organ of our body hence limitless diversity of the various types of lesions leaves a general pathologist struggling this diversity ranges from allergic inflammatory bullous to melanocytic and non melanocytic neoplasms including a wide variety of adnexal tumours. An understanding of normal skin histology is essential in dermatopathology this chapter introduces fundamental terms used to describe skin pathological changes acanthosis describes thickening of the epidermis it is classified into flat psoriasiform papillomatous and pseudocarcinomatous. This article will describe the anatomy and histology of the skin undoubtedly the skin is the largest organ in the human body literally covering you from head to toe the organ constitutes almost 8 20 of body mass and has a surface area of approximately 16 to 18 m2 in an adult. 1 panniculitis 2 other changes in fat tissue
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